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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12001/4151

 
Title :[原著]Lennox 症候群 : 自験6症例の検討
Title alternative :Six Cases of Lennox Syndrome
Authors :崎山, 慧史
佐久川, 肇
Authors alternative :Sakiyama, Satoshi
Sakugawa, Hajime
Authors affiliation :琉球大学医学部附属病院精神科神経科
Issue Date :1982
Publisher :琉球大学医学部
Type Local :雑誌掲載論文
Type (NII) :Journal Article
ISSN :0285-9270
Abstract :Six cases ( 3 boys, 3 girls ) of Lennox syndrome which were surveyed in our clininc, between April 1975 and December 1981, were investigated from the viewpoint of the various clinical aspects and the following results were obtained. The age of each case at the onset were between 0 and 5 years in all cases, specially before 1 year in 2 cases. The seizure patterns at the onset were grand mal in 3 cases, tonic spasms with series ( West syndrome ) in one case, without series in 2 cases, one tonic spasms and the other atonic seizure. The underlying pathologies were observed in 3 cases; moderate mental retardation, cerebral palsy with severe mental retardation and tuberous sclerosis ( suspected ) As to the minor seizures, tonic spasms were recognized in 5 cases, tonic sezure in 4 cases, atypical absence in 5 cases, myoclonic seizure in 3 cases and atonic seizure in 2 cases. The EEG showed diffuse slow wave dysrhythmia as basic pattern and diffuse slow spike and wave as interictal seizure discharge in all cases. The diffuse slow spike and wave were classified into typical in 2 cases, disorganized in one case, asymmetric in one case and focalization type in 2 cases. The activation of seizure discharge was obtained by natural sleep, but not by hyperventilation or photic stimulation. The ictal EEG showed desynchronization in one case, rapid synchronization in 2 cases and recruiting rhythm in 2 cases. Rapid rhythm was observed during moderate to deep sleep in 3 cases. The CT scan showed abnormal findings in 3 cases ; calcifications in 2 cases and moderate ventricular dilatation in one case. All were mental handicaped cases. Follow-up study indicated the refactoriness to therapy of anticonvulsant. 5 cases remained the minor seizures, one case of them was dead of fulminant hepatitis and only one case became free from seizures.
Rights :琉球医学会
URI :http://hdl.handle.net/20.500.12001/4151
Citation :琉球大学保健学医学雑誌=Ryukyu University Journal of Health Sciences and Medicine Vol.4 no.4 p.337 -349
Appears in Collections:Ryukyu University Journal of Health Sciences and Medicine

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