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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12001/3276

Title :[症例報告]A Case of Paraneoplastic Cerebellar Degeneration in Small Cell Lung Cancer : Autopsy Findings after Chemoradiotherapy
Authors :Kuda, Tomoharu
Ichinose, Yukito
Kawasaki, Masayuki
Hara, Nobuyuki
Authors affiliation :Department of Chest Surgery, National Okinawa Hospital, Okinawa, Japan
Department of Chest Disease, National Kyushu Cancer Center, Fukuoka, Japan
Issue Date :1994
Publisher :琉球医学会
Type Local :雑誌掲載論文
Type (NII) :Journal Article
ISSN :1346888X
Abstract :The patient was a 62-year-old man with small cell lung cancer(SCLC). Symptoms such as dizziness, ataxia and double vision developed in the course of preoperative chemotherapy of cisplatin and VP-16. Despite the chemoradiotherapy, disabling cerebellar dysfunction developed rapidly, and operation was canceled due to poor performance status. The patient died 6 weeks after onset of the symptoms. Diagnosis of paraneoplastic cerebellar degeneration (PCD) was confirmed by autopsy which revealed a decreased number, not total loss, and degeneration of Purkinje cells in the cerebellum. Surgery could have been carried out had it not been for the cerebellar dysfunction since the cancer was at an early stage and the loss of Purkinje cells was not complete.
Rights :琉球医学会
URI :http://hdl.handle.net/20.500.12001/3276
Citation :琉球医学会誌 = Ryukyu Medical Journal Vol.14 no.3 p.209 -211
Appears in Collections:Ryukyu Medical Journal

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