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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12001/3267

 
Title :[症例報告]縦隔原発非精上皮腫性胚細胞性腫瘍の1例
Title alternative :Mediastinal Non-Seminomatous Germ Cell Tumor : A Case Report
Authors :川畑, 勉
城間, 寛
鎌田, 義彦
佐久田, 斉
玉木, 正人
砂川, 一哉
下地, 光好
宮城, 和史
赤崎, 満
伊波, 潔
国吉, 幸男
古謝, 景春
草場, 昭
岩政, 輝男
Authors alternative :Kawabata, Tsutomu
Shiroma, Hiroshi
Kamada, Yoshihiko
Sakuda, Hitoshi
Tamaki, Masato
Sunagawa, Kazuya
Shimoji, Mitsuyoshi
Miyagi, Kazufumi
Akasaki, Mitsuru
Iha, Kiyoshi
Kuniyoshi, Yukio
Koja, Kageharu
Kusaba, Akira
Iwamasa, Teruo
Authors affiliation :琉球大学医学部外科学第二講座
琉球大学医学部病理学第二講座
Issue Date :1994
Publisher :琉球医学会
Type Local :雑誌掲載論文
Type (NII) :Journal Article
ISSN :1346888X
0289-1530
Abstract :A 16-year-old male patient was referred to our hospital because of left supraclaviclar lymphnode swelling and a mediastinal mass on chest X-ray film. The serum HCG, AFP and NSE values were extremely elevated. No abnormality was found in the testis. Chemotheapy with CDDP, VP-16 and BLM was begun immediately after supraclaviclar lymphnode biopsy indicated choriocarcinoma. After two courses of chemotherapy, the supraclaviclar and mediastinal mass were markedly decreased in size and the serum tumor markers normalized. Following chemotherapy, the residual tumors were extirpated and regional lymphnodes were dissected. The primary tumor consisted of necrotic tissue, and in the metastatic lesion, viable malignant cells were seen. Postoperatively, one course of the same chemotherapy as before surgery was added. Six months after discharge, lung metastasis with reelevation of serum HCG level was seen. The patient died 18 months after initial treatment. Mediastinal malignant germ cell tumor progresses so rapidly and its prognosis is so poor that aggressive multimodal therapy seems to be necessary.
Rights :琉球医学会
URI :http://hdl.handle.net/20.500.12001/3267
Citation :琉球医学会誌 = Ryukyu Medical Journal Vol.14 no.4 p.263 -267
Appears in Collections:Ryukyu Medical Journal

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