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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12001/24892

Title :集学的治療により切除しえた乳腺巨大葉状腫瘍の1例
Title alternative :A case of a giant phyllodes tumor of the breast successfully resected with multimodal therapy
Authors :藤澤, 重元
國仲, 弘一
牧野, 航
平安名, 常一
高槻, 光寿
Authors alternative :Fujisawa, Shigemoto
Kuninaka, Kouichi
Makino, Wataru
Heianna, Joichi
Takatsuki, Mitsuhisa
Authors affiliation :Department of digestive and general surgery, University of the Ryukyus Hospital,
Department of Radiology, University of the Ryukyus Hospital
Issue Date :2020
Publisher :琉球医学会
Type Local :雑誌掲載論文
Type (NII) :Journal Article
ISSN :1346-888X
Abstract :A 43-years-old woman presented with a giant light breast tumor that had grown approximately 3-25cm in diameter over the past two years. The tumor was elastic, hard, and had enlarged skin and was fixed on chest wall with poor mobility. Chest computed tomography(CT) scan revealed a giant tumor with thoracic wall and skin as well as, nipple invasion, without swollen axillary lymph nodule and distant metastasis. A diagnosis of giant phyllodes tumor was made. To avoid thoracic wall resection, we used Eribulin regimen for three courses as preoperative chemotherapy and performed selective intra-arterial chemotherapy (internal thoracic artery, thoracromial artety, lateral thoracic artery) with Docetaxel and Epirubicin and embolization with Embosphire for two times at, four weeks interval. Chest CT in two weeks revealed tumor shrinkage from 15.1×7.5cm to 13.4×6.3cm. We planned to revise the operative procedure, depending on surgical margin by intraoperative consultation. With surgical positive margin, we planned to perform mastectomy and thoracic wall resection, reconstruction by latissimus dorsi musculocutaneous flap, skin grafting on the defected area. With surgical negative margin, perform mastectomy and skin grafting on defected area. As surgical margin was negative, we performed mastectomy and skin grafting from outside of the right thigh, in four weeks following the last selective intra-arterial chemotherapy and embolization. The resected tumor weighed 1100g and ,measured 21.2×18.0×7.5cm. We report the present case alongside a review of the literature and discuss the preoperative chemotherapy and selective intra-arterial chemotherapy and embolization as well as the operative procedure.
Rights :琉球医学会
URI :http://hdl.handle.net/20.500.12001/24892
Citation :琉球医学会誌 = Ryukyu Medical Journal Vol.39 no.1-4 p.49 -58
Appears in Collections:Ryukyu Medical Journal

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