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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12001/2286

 
Title :[症例報告]上咽頭癌に対する照射前化学療法
Title alternative :Pre-radiotherapy Chemotherapy for Nasopharyngeal Carcinoma
Authors :末山, 博男
諸見里, 秀和
滝沢, 義和
堀川, 歩
中野, 政雄
Authors alternative :Sueyama, Hiroo
Moromizato, Hidekazu
Takizawa, Yoshikazu
Horikawa, Ayumi
Nakano, Masao
Authors affiliation :琉球大学医学部放射線医学
Issue Date :1991
Publisher :琉球大学医学部
Type Local :雑誌掲載論文
Type (NII) :Journal Article
ISSN :0289-1530
Abstract :Three cases of carcinoma of the nasopharynx were treated with combination chemotherapy (Cisplatin [CDDP]+5-Fluorouracil[5-FU]) and sequential radiation therapy.All cases were male and the mean age 56 years. The histology was poorly differentiated squamous cell carcinoma in all three patients. in accordance with the UICC System (1978), the three cases were classified T2NO, T3NO and T3N2. Preradiotherapy chemotherapy was administered containing CDDP and 120-hour continuous infusion of 5-FU. One patient achieved a complete response (CR) and two patients a partial response after two or three cycles of chemotherapy. Radical radiotherapy was performed within two weeks after the last course of chemotherapy. Radiation toxidty was mild and no increase in morbidity was observed after the combination chemotherapy. All three patients achieved CR in definitive treatment. 35 months later, there is no evidence of recurrence. Thus our conclusion is that preradiotherapy chemotherapy is effective in patients with nasopharyngeal carcinoma.
Rights :琉球医学会
URI :http://hdl.handle.net/20.500.12001/2286
Citation :琉球大学医学会雑誌 : 医学部紀要 = Ryukyu medical journal Vol.11 no.3-4 p.165 -171
Appears in Collections:Ryukyu medical journal

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