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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12001/22210

Title :集学的治療により長期生存が得られたS状結腸癌術後再発の1例
Title alternative :A case of sigmoid colon cancer peritoneal dissemination recurrence was received multimodal therapy and had a long time survival.
Authors :伊禮, 靖苗
金城, 達也
金城, 章吾
佐村, 博範
西垣, 大志
西, 巻正
Authors alternative :Irei, Yasue
Kinjo, Tatsuya
Samura, Hironori
Nishigaki, Taishi
Kinjo, Shogo
Nishimaki, Tadashi
Authors affiliation :琉球大学大学大学院消化器・腫瘍外科学講座
Issue Date :28-Oct-2016
Publisher :琉球医学会
Type Local :雑誌掲載論文
Type (NII) :Journal Article
ISSN :1346-888X
Abstract :62-year old woman with stage Ⅱ sigmoid colon cancer underwent sigmoidectomy with D3 lymphadenectomy at another hospital in December 2004. One year later, she experienced atypical genital bleeding. She was referred to our hospital for examination and treatment. She was diagnosed with a peritoneal recurrence of sigmoid colon cancer, with disseminated nodules that had invaded the intestinal wall and uterus. High anterior resection, total abdominal hysterectomy, and bilateral salpingo-oophorectomy were performed, subsequent histopathological examination revealed a well-differentiated adenocarcinoma. Because carcinoembryonic antigen (CEA) levels were increased rapidly after adjuvant chemotherapy, she received bimonthly oxaliplatin plus infusion fluorouracil with leukovorin regimen (mFOLFOX6). Although mFOLFOX6 8 courses were administered, computed tomography (CT) showed disseminated nodules, ranging in size from 7 to 30 mm, at the pelvic floor, around the anastomosis site, in the mesentery of the small intestine and in the greater omentum. In July 2007, Hartmannʼs operation, partial resection of the small intestine, and greater omentum, left ureterovesical anastomosis, and hyperthermic intraperitoneal chemotherapy was performed. Histopathological examination revealed a well-differentiated adenocarcinoma. Bimonthly irinotecan plus infusion fluorouracil with leukovorin regimen (FOLFIRI) 20 courses and Tegafur-uracil (UFT) following FOLFIRI were administered as adjuvant chemotherapy. In February 2010, CT showed disseminated nodules at near the stump of rectum, right side of urinary bladder. Then, peritoneal metastasectomy was performed. Histopathological examination revealed a moderately differentiated adenocarcinoma. She was disease-free for 5 years after the last surgery. We reported a case of patient with peritoneal recurrence of sigmoid colon cancer that received multidisciplinary treatment and remained disease free for a long duration. And we also reviewed previous studies and case reports.
Rights :琉球医学会
URI :http://hdl.handle.net/20.500.12001/22210
Citation :琉球医学会誌 = Ryukyu Medical Journal Vol.35 no.1-4 p.57 -64
Appears in Collections:Ryukyu Medical Journal

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